Crew members left constantly during production. Whoopi Goldberg once said that on her final day of shooting, 99% of the crew was different from the first day.

Rex was originally intended for theatrical release. But the movie tested poorly with older test audiences. So the studio released it straight-to-video in the US, where it could make more money in the lucrative kids' video market. Since the movie was completed on it's original theatrical studio budget, Rex became the most expensive straight-to-video film ever at the time of its release. It was, however, shown theatrically in many countries around the world including Germany, Spain, France, Japan, Portugal, UK and South Africa.

Whoopi Goldberg wanted to leave the film during the production.

Whoopi Goldberg made a verbal agreement to star in the film in 1993. When she tried to back out, producer Richard Gilbert Abramson sued her for $20 million. The suit was settled very quickly, when Goldberg agreed to star for $7 million, $2 million more than the original agreement.

Most of the actors signed on thinking the dinosaur would be computer enhanced.

Jonathan R. Betuel retired from directing after this film. He felt the studio didn't market it correctly.

The first and only (as of 2012) direct-to-video film to be nominated for a Razzie.

William Boyett's final film.