Originally there were going to be four teams instead of the three that appeared on the show. The fourth team was going to be called the Dabba Doozies and they were going to be captained by the teen-aged Pebbles and Bamm Bamm and some of the members of that team were to have been Touche Turtle, Lippy the Lion, Judy and Elroy Jetson and their dog Astro, Jabberjaw, Magilla Gorilla, Peter Potomus, Top Cat and Tom and Jerry. However, it was felt that with so many other characters, there was no need for a fourth team.

Mumbley and the Dread Baron were added to the Really Rottens to replace Muttley and Dick Dastardly, who were not owned by Hannah-Barbara. Dastardly and Muttley were owned by Heatter-Quigley productions. Fondu may have been a replacement as well.

Jeannie (1973) from the cartoon as well as Alex and Alexandra Cabot and Melody from Josie and the Pussycats (1970) were originally set to appear on the show as members of the Scoobies. In fact, they were even in some of the early promotional ads for the show. However, the character of Jeannie was owned by Columbia Pictures and Alex, Alexandra and Melody were owned by Archie Comics and because of this they were not allowed to be on the show.

The series was to originally feature characters from Josie and the Pussycats (1970), who were seen in early promotional art for the show. Due to legal disputes between Hanna-Barbera and Archie Comics, the Josie characters couldn't be used and were replaced by Captain Caveman and the Teen Angels. There also was a dispute with Columbia Pictures television over the character Jeannie. However, because the character Babu was a Hanna-Barbera creation he was allowed to appear on the show.

While throughout the years Hanna-Barbara made dozens of crossover cartoons with characters from different cartoon series. This is the only time characters from the four most notable Hanna-Barbara franchises ever (Scooby-Doo, The Yogi Bear Show, The Huckleberry Hound Show and The Flintstones) interact with each other.

The Yogi Yahooies team was made up of Hanna-Barbera's 1950's/60's era anthropomorphic animal characters, while the Scooby Doobies team consisted of the studio's 1970's era mystery solving characters.

Snagglepuss and Mildew Wolf, who served as Sideline Reporters/Color Commentators were seen wearing bright yellow colored jackets, similar to those worn by ABC Sports on-air personnel, as ABC broadcast the series.

Originally, Hong Kong Phooey and Spot were going to be referees, but Spot was dropped and Phooey was added to the Scooby Doobies.

Although this show was made and aired originally as a Saturday morning cartoon, Teletoon used to air it on weekdays following the last of their original Scooby-Doo episodes.

The Great Fondue, the evil magician whose tricks and spells never worked as intended and always backfired, was based on Abner K. Dabra from the 1963 book Yogi Bear and the Cranky Magician.

Magic Rabbit, pet of the Great Fondue who mostly quotes "Brak", was based on the White Rabbit from Alice in Wonderland or What's a Nice Kid Like You Doing in a Place Like This.

Daisy Mayhem was based on Mean-spirited hillbilly with split ends in her hair "Moonbeam McSwine" character from the "Li'l Abner" comic strip.