Nishana is the first hindi film of Director K.Raghavendra Rao who is called Manmohan Desai of south and also the producers of this film, this was their first hindi production the same team later made Farz Aur Kanoon with Jeetendra, Hema Malini, Raj Kiran and Rati Aghnihotri.
Amjad Khan claimed he was to do the main villain's role. But later the director changed his mind as he felt Amjad was too large for Jeetendra to fight. The fight scenes would be unconvincing.
Only movie where Poonam Dhillon played Jeetendra's full-fledged heroine. She was young, Noorie was a super hit and the South producers were keen to cast her opposite him. The movie bombed and the pair did not take off. Poonam played a supporting role in Himmat aur Mehnat, Jai Shiv Shankar and Mahanta though she was romantically paired with him.
Rivals Jeetendra and Amitabh Bachchan clashed at the box office as both Dostana and Nishana released on the same day in 1980.
Film was released during Dussehra festival in 1980.