Though 'Get a Clue' was set in New York City, the school that the characters attend is filmed at the Bishop Strachan School in Toronto, Canada which is a real private school.

This is the last film that Lindsay lohan stars in under her original disney contract that required her to do 3 movies.

In 2005, Disney Channel had a special event naming the five best Disney Channel Original Movies which led to the premiere of their new movie, Go Figure. This film placed number two by viewers with Stuck in the Suburbs at 5, Gotta Kick it Up at 4, Halloweentown High at 3, and the Cheetah Girls at 1 as of summer of 2005.

A song by the band Prozzak, "Get a Clue", appeared in the film and the music video was shown on Disney Channel at the time of its release. The name of the band was changed to "Simon and Milo", the characters depicted in the music video so their band name would not be associated with the drugs.

A well-concealed reshoot took place in late 2001 to film a different ending concluding that the villain in the film was Meany. In the original ending, the villain turned out to be Mrs. Stern, a teacher at Lexy's school who had known Mr. Walker while he was living in Arizona.