When Van Ruijven comes to dinner, to discuss a new commission for Vermeer, he grabs Griet and she drops the dishes she is carrying. She leans down to pick them up placing a broken piece on top of one that isn't. When she stands back up neither plate she has in her hand is broken.
When Griet first hears the rumors about herself, her cap changes from square flaps (walking to the market) to pointed flaps (talking to Pieter the butcher's son at the market) and back to square flaps again (talking to Vermeer and his patron back at home again).
As Vermeer starts to paint Griet he is wearing a shirt that ties at the collar. At the easel it is tied loosely in a double knot baring some of his upper chest. When Griet goes into the storeroom and Vermeer follows and stares at her the strings of the shirt are now tied tightly to his neck.
When Griet and Vermeer look at the clouds standing in front of the window, it's winter (according to the scenes before and after this one). Nevertheless, you can hear the sounds of swallows squeaking. These birds are only in The Netherlands in summer.
In the movie, Vermeer uses the painting "The Procuress" as a prop in a handful of paintings. However, in the movie, the painting has different dimensions then in the actual painting.
The hands cutting the vegetables at the beginning of the movie are not Scarlett Johansson's hands.
Whilst looking at the clouds out of the window together, both Scarlett Johansson (Griet) and Colin Firth (Vermeer) are visibly trying to stop themselves from giggling.
When Griet and Pieter are walking on a lane in the countryside, in the distance you can see a man riding a bicycle. Bicycles were invented in the 18th century while the film takes place in 1665.
When Griet has just been shown around the house, she descends a staircase holding what looks like a hurricane lamp with a flame enclosed in glass. This kind of lamp was not invented till the 19th century, some 200 years after the painting was created.
The camera obscura is partially made of plywood, which was invented in the 1930s.