Ayako Kawasumi, who plays Mahoro, sings the show's opening songs "Kaerimichi" and "Soreiyu". Asami Sanada, Manabi Mizuno and Yumi Kikuchi, who play the three friends Chizuko, Rin and Miyuki, sing the show's ending songs "Mahoro de Mambo" and "Triomatic Ran! Ran! Ran!".

The show's title "Mahoromatic" is a portmanteau of the name "Mahoro" and "automatic" (as in Mahoro the Automatic). Asami Sanada, Manabi Mizuno and Yumi Kikuchi, who play the three friends Chizuko, Rin and Miyuki, are also credited as the music group Triomatic.