Patrick Dempsey, Justin Chambers, Melissa George, Sandra Oh, and Ellen Pompeo in Grey's Anatomy (2005)

Eric Stoltz and Melissa George in Grey's Anatomy (2005)

Melissa George, Sandra Oh, and Ellen Pompeo in Grey's Anatomy (2005)

Katherine Heigl and Justin Chambers in Grey's Anatomy (2005)

Patrick Dempsey and Chyler Leigh in Grey's Anatomy (2005)

Eric Dane, Chyler Leigh, and Ellen Pompeo in Grey's Anatomy (2005)

Justin Chambers and Sandra Oh in Grey's Anatomy (2005)

Sandra Oh and Ellen Pompeo in Grey's Anatomy (2005)

Jesse Williams, Chris Carmack, and Jaicy Elliot in Grey's Anatomy (2005)

Sandra Oh, James Pickens Jr., Sara Ramirez, and Scott Garfield in Grey's Anatomy (2005)

Jessica Capshaw, Sara Ramirez, and Chandra Wilson in Grey's Anatomy (2005)

Sarah Drew and Carly Peeters in Grey's Anatomy (2005)

Mandy Moore and Chandra Wilson in Grey's Anatomy (2005)

Debbie Allen and James Pickens Jr. in Grey's Anatomy (2005)

Caterina Scorsone in Grey's Anatomy (2005)

Rachel Brosnahan in Grey's Anatomy (2005)

Ellen Pompeo and Josh Radnor in Grey's Anatomy (2005)

Ellen Pompeo and Jaicy Elliot in Grey's Anatomy (2005)

Kevin McKidd and Ellen Pompeo in Grey's Anatomy (2005)

Jessica Capshaw and James Pickens Jr. in Grey's Anatomy (2005)

Jessica Capshaw and Caterina Scorsone in Grey's Anatomy (2005)

Patrick Dempsey and Ellen Pompeo in Grey's Anatomy (2005)

Justin Chambers and T.R. Knight in Grey's Anatomy (2005)