Partly based on the original, much longer script for Day of the Dead (1985).

At the beginning of the movie, if you listen carefully to the tuba and tambourine zombies in the town bandstand, they are playing notes from "The Gonk", the mall music from George A. Romero's Dawn of the Dead (1978).

There were four titles before "Land of the Dead" was chosen: "Dead City", "Dead Reckoning", "Twilight of the Dead", and "Night of the Living Dead: Dead Reckoning".

George A. Romero was so impressed with Simon Pegg and Edgar Wright's Shaun of the Dead (2004), that he asked them to appear in this, the fourth part of his "Dead" series, and they appear as the photo-booth zombies in the carnival and barroom sequence. They also feature prominently in the artwork for the Unrated Director's Cut.

The zombie of Tom Savini's biker character, who was killed in Dawn of the Dead (1978), can be seen in one of the scenes.

George A. Romero's daughter appears in the film. She is the soldier who shoots the zombie on the electrified fence.

An amputee played the legless zombie climbing the back of the Dead Reckoning. His name is David Campbell, and was also in Dawn of the Dead (2004) as the "Squished Zombie".

The view of the zombies rising from out of the river is an homage to the classic scene from Herk Harvey's Carnival of Souls (1962), where the dead rise out of the Great Salt Lake before the dance sequence.

The opening credits includes a montage detailing the zombie outbreak leading up to the events of this film, with black and white footage and radio broadcasts depicting the infection's spread over the Earth. Some of the images come from George A. Romero's Night of the Living Dead (1968) portraying the beginning of the outbreak. Romero wanted to use more footage from the other two films of the series up to that point, Dawn of the Dead (1978), and Day of the Dead (1985), but was unable to due to complications with the rights of those films. This is because each of his zombie films have been produced by different studios. This can also be seen in the credits for Tom Savini's cameo in the film. He is the undead version of the character he portrayed in Dawn of the Dead (1978), named "Blades", but he could only be credited in this film as "Machete Zombie".

This movie's Pittsburgh premiere was at the Byham Theatre, which used to be called the Fulton Theatre. This theater, when it was still the Fulton, was the same theater where Night of the Living Dead (1968) premiered in 1968.

George A. Romero intended to make this film in his hometown of Pittsburgh, Pennsylvania. The story is set there, and it's where he made his other zombie films. However, the producers insisted on filming in Toronto, Ontario, in order to take advantage of Canadian tax incentives, creating a setting that retains Pittsburgh's geography, with physical locations of Toronto that have been altered.

A non-union zombie would make nine dollars per hour Canadian, while a union zombie, for a minimum of eight hours, would make one hundred fifty-eight dollars Canadian.

This is the fourth film in George A. Romero's zombie series, which Romero says takes place after Night of the Living Dead (1968) with no specific time frame. The last zombie film he wrote and directed was Day of the Dead (1985).

One working title for the film was "Dead Reckoning", but it was changed to avoid confusion with the Humphrey Bogart film of the same name.

This is the first film of George A. Romero's "Living Dead" series which uses digital effects.

Dennis Hopper based his performance as Kaufman on Donald Rumsfeld.

DIRECTOR CAMEO (George A. Romero): His voice can be heard as one of the puppets in the children's show, saying, "Take that, you smelly zombie!"

The first trailer for this film used clips not just from Night of the Living Dead (1968), but also from Dawn of the Dead (1978), and Day of the Dead (1985), Although Night is in the public domain, both Dawn and Day are owned by separate companies, neither of which had given permission for the use of footage in the trailer. To avoid legal troubles, this trailer was quickly pulled from distribution, and hasn't been officially shown since.

Asia Argento (Slack) is the daughter of noted Italian horror filmmaker Dario Argento, who was the co-producer and co-composer of one of the previous entries in George A. Romero's zombie series, Dawn of the Dead (1978).

"Fiddler's Green" is a song about the place where cavalrymen go when they die, located "Halfway down the trail to Hell", and, in the end, advocates suicide by pistol when death is certain, and the hostiles are closing in. "Fiddler's Green" possibly originated in England at least to the nineteenth century, and is still sung today. The song speaks of a place where fisherman go, if they don't go to Hell. It found its way to the U.S. with the help of Cornish settlers. The fictional place of Fiddler's Green is also the final resting place for pirates.

Second movie, in which John Leguizamo and Dennis Hopper appear, the other is Super Mario Bros. (1993).

John Leguizamo's character's name "Cholo" is a pejorative word used in South American Spanish to refer to Ecuadorians, Peruvians, and Bolivians, who have strong Indian features.

Dennis Hopper and Robert Joy previously appeared in Waterworld (1995). In that movie, Hopper's character licks his thumb and touches his rifle's sight before taking a shot. This is also a signature quirk of Charlie (Robert Joy) in this movie.

Susan Wloszczyna, a reporter for USA Today, appeared as one of the zombies. She was there interviewing her fellow zombies, as well as the director. She spent nearly an hour and forty-five minutes in the make-up chair.

The name of the military vehicle mainly used in the movie is the "Dead Reckoning", one of the film's working titles.

The first and, to date, only George A. Romero zombie film to use the 2.35:1 aspect ratio. The other films used standard 4:3 or Flat Ratios. Night of the Living Dead (1968) (1.33:1), Dawn of the Dead (1978) (1.85:1), Day of the Dead (1985) (1.85:1), and Diary of the Dead (2007) (16:9 a.k.a. 1.78:1).

The rifle carried by Charlie (Robert Joy) is an M-1 Carbine, a weapon developed during World War II. It was noted for its superb accuracy (for a carbine), and also hated by the Marines for its puny stopping power.

Alan Van Sprang and Shawn Roberts are the only two Land actors to carry over to another "Dead" movie by playing different characters. Alan Van Sprang was in Land of the Dead (2005) as a soldier named Brubaker, who died and became a zombie, and he was Sarge in Diary of the Dead (2007), and Survival of the Dead (2009). Whereas Shawn Roberts played a rookie called Mike, in Land of the Dead (2005), and one of the students named "Tony Ravello" in Diary of the Dead (2007).

Movie theaters showing this film in the U.S. were given a replacement track for the typical music and commercials usually heard playing over still images of advertisements before a movie starts. This track consisted of sound bites of music and lines from Night of the Living Dead (1968), and Day of the Dead (1985), along with an advertisement for then upcoming airings of Day of the Dead (1978) on a pay-per-view network.

The assault rifle Big Daddy (Eugene Clark) finds is an Austrian Steyr Aug.

The shoulder holster in which Cholo carries his pistol is a Galco model called "The Executive".

Sasha Roiz (Manolete the "Bullfighter") starred alongside Simon Baker (Riley) as a politician in The Mentalist (2008).

The success of Zack Snyder's remake of Dawn of the Dead (2004) led Universal to greenlight a fourth instalment of George A. Romero's zombie series.

The most expensive of George A. Romero's zombie movies.

George A. Romero was initially in negotiations with 20th Century Fox who wanted to call it "Night of the Living Dead". Romero refused as that of course was the title of the first film in his series.

This is the first film in the series to be released with an MPAA rating.

Banned in Ukraine.

Simon Baker took on his role in the film because he'd never appeared in a horror movie before and because he wanted to work with George A. Romero.

In later interviews, George A. Romero implied that Dennis Hopper's cigar budget cost more than his original Night of the Living Dead (1968).

Boyd Banks: Boyd Banks, the actor who played Tucker in Dawn of the Dead (2004), and "White Man" in George A. Romero's Diary of the Dead (2007) also plays "the butcher" in this movie.

In the scene where the zombies get into the city, the soldier playing cards, who has his head pulled off, his camouflage uniform says "Rickles" in the name area. Rickles was the name of one of the soldiers from Day of the Dead (1985).