Actress Kim Rhodes is notorious for her "potty mouth" and consistently sweared on set. One of the Disney Channel representatives suggested having a "swear jar" on the set. Dylan Sprouse responded, "We've worked with Adam Sandler. We've heard it all!"
Dylan and Cole Sprouse, Phill Lewis, and Kim Rhodes are the only cast members to appear every episode.
One of the executive producers pulled Becky Rosso and Milly Rosso from the audience to play the twins' girlfriends.
Brenda Song's character of "London Tipton," the hotel owner's spoiled daughter, is an obvious play on hotel heiress Paris Hilton.