The character of "D.B. Cooper" is based on an actual person, who in 1971, after hijacking an airliner, extorted $200,000 from its owner, Northwest Orient, and leaped off the airborne plane with 21 pounds of $20 bills strapped to his body. He was never found. The theory is that he was killed because his parachute didn't deploy.

Thirteen prisons banned this show.

It took 4.5 hours to apply the tattoo to Wentworth Miller on set.

Wentworth Miller was a last minute casting choice. He started filming about a week after auditioning/being cast.

Several characters are named after presidents and politicians. Lincoln Burrows and Theodore "T-Bag" Bagwell are named after Presidents Abraham Lincoln and Theodore Roosevelt. Michael Scofield, Benjamin Miles "C-Note" Franklin and Alexander Mahone are named after politicians Edward Scofield, Benjamin Franklin and William Mahone. Also Paul Kellerman is named after Roy Kellerman, the Secret Service agent who was riding in President John F. Kennedy's limousine at the time of his assassination.

On August 6, 2015 FOX officially announced there will be a Season 5 continuation of Prison Break (2005).

Paul Scheuring had said that the initial concept for the series (a man deliberately getting himself sent to prison in order to break out again) was suggested to him by a female colleague of his (Dawn Parouse). He thought it was a great idea, but was initially stumped as to why someone would embark on such a strange mission or how he could stretch the idea out long enough for a TV show. He later came up with the idea of the wrongfully accused brother, and the conspiracy subplot. He then started work on writing the pilot script for the show.

Stacy Keach (the Prison Warden) spent six months in a British prison and modeled his character after the man in charge at that institution.

Wentworth Miller and Dominic Purcell play brothers in the show. They reunite as partners in crime in The Flash (S01E10), as Captain Cold and Heat Wave. They make several subtle references to Prison Break.

Michael Scofield's tattoo was designed by tattoo artist Tom Berg. Berg was asked to work on the show by Brett Ratner after previously designing the tattoo for the character of Francis Dolarhyde in Ratner's film Red Dragon (2002). Berg estimated that to get the tattoo done for real would take four years and would cost between fifteen and twenty thousand dollars. Berg also designed Haywire's sketches of the tattoo.

Many of the scenes are filmed on location in the actual cell that housed John Wayne Gacy.

It was originally between Johnny Messner & Eric Dane for the role of ''Lincoln Burrows'' in Prison Break, Fox couldn't decide between them and they went with Dominic Purcell instead.

The 4-month hiatus between the airing of episodes 13 and 14 came back to haunt the producers. Lincoln's execution was scheduled to take place in May. All of a sudden it was snowing.

Silas Weir Mitchell (Haywire) originally auditioned for the role of T-Bag.

Thirteen episodes had originally been ordered but due to the success of the show, Fox extended it to a full season.

A 5th season was confirmed on October 18th 2015

If you were to have a tattoo like Michael's, it would take around 200 hours to make and it would cost around $15,000-$20,000.

The filming location, the old Joliet Prison, actually only has cells stacked two high. To be able to show the cells stacked three high, a studio set was constructed.

'Sarah Wayne Callies' was the first actor to be cast.

In Season 3, the two main characters, "T-Bag" and "Sucre," meet with the character "Lechero." If you take all their names, you get the main ingredients to make tea. T-bag, obviously, sucre is French for sugar and lechero is milkman.

Robert Knepper (T-Bag) says he based the haircut of his character on an old science teacher he had, who had a "poofy bit," which always stuck up at the front.

According to an interview with Rockmond Dunbar the character of C-Note was only supposed to appear in the first 2 episodes but when the show was renewed for a full season C-Note's role was extended to a recurring character.

The reflection sequence in Season 1, Episode 20 contains the theme song from the Fox tv show House M.D., which Wentworth Miller, Dominic Purcell, Sarah Wayne Callies, and Robin Tunney separately guest starred on.

The idea for the show was originally pitched to the Fox Broadcasting Company in 2003 but was turned down as Fox felt somewhat nervous about the long-term possibilities of such a television series. It was later considered as a possible 10-part mini series, which allegedly drew interest from big names in the film industry such as Steven Spielberg and Bruce Willis. However, the mini series never materialized. Following the huge popularity of serialized prime-time television series such as 24 (2001) and Lost (2004), the Fox Network had a change of heart and backed the production in 2004.

The electric chair is not used as a primary instrument of execution in the State of Illinois where the series is set. Originally, the method of execution scripted for Lincoln's death was via lethal injection. For shock value, however, this was changed to the electric chair. The State of Illinois currently has a moratorium on the death penalty.

Nadine Velazquez played Maricruz Delgado in the pilot but was unable to appear in the series as she had signed on to appear in My Name Is Earl (2005) before the show was commissioned. She was replaced by Camille Guaty.

The name of the prison in the show, Fox River, shares the name of a river that runs through Western Chicagoland, near the real prison filming location.

Wentworth Miller had previously auditioned for 'Superman: Flyby', a film which Brett Ratner was to direct but which was ultimately never made. Ratner was impressed by Miller's audition and recommended him to the producers of the show.

Wentworth Miller and Dominic Purcell are very close friends in real life. They also portray criminal partners Captain Cold and Heatwave in the The Flash (2014) and its spin-off, Legends of Tomorrow (2016). They are actually responsible for the creation of this 5th season: while working together on the set of Legends of Tomorrow (2016), Purcell suggested a reboot of the series to Miller. Miller agreed, took the idea to Fox, pitched it as a series, and the network picked it up.

Wentworth Miller and Dominic Purcell also appear together in the CW shows The Flash (2014) and Legends of Tomorrow (2016)

Wentworth Miller and Dominc Purcell are also starring together on "Legends of Tommorow". Wentworth playing Leonard Snart (aka Captain Cold) and Dominic Purcell playing Mick Rory (aka Heat Wave).

In a draft pilot dated December 2003; the prison was set to be the Real Life 'Supermax' Wallens Ridge Prison in Virginia, it was supposed to have a 60 minute run time, not the ~40 minutes it eventually did. Scofield's 'back number' was 55241, not 94941. Sucre's friend in the Prison Yard was C-Note, this changed to a different character called 'Wholesale'. Fibonacci was called Hill. Scofield was top of his class at Georgetown not Loyola. Scofield getting caught with the shank after the toilets were blocked off was in this episode, this was switched with Scofield attacking Abruzzi to lead to a second meeting with Pope.

Both Jeff Perry (the Vice Presidents brother, Terrence Steadman) and Paul Adelstein (the Vice Presidents bodyguard, Paul Kellerman) play roles in Scandal, which also deals with a government conspiracy.

According to an Instagram post from Dominic Purcell (posted in December 2017) Season 6 of Prison Break is currently in the works.

Both Wentworth Miller (Michael) and Dominic Purcell (Lincoln) played parts on single seperate episodes on House MD. Wentworth was on "Charity Case" (08x3) and Dominic was on "Fidelity" (01x7).

Three characters from Season 1 go on to play characters in the show Chicago Fire, also based in Illinois. DuShon Monique Brown who plays Nurse Katie Welch goes on to play Connie, the firehouse secretary. Christian Stolte who plays Corrections Officer Keith Stolte goes on to play Randall "Mouch" McHolland. Joe Minoso who plays Chaz Fink, the video analyst, goes on to play Joe Cruz.

Amaury Nolasco (Sucre) and Wade Williams (Bellick) share the same birthday which is December 24.

During the first episode of Season 5 the man in the 'fake' images of Michael online, is Paul Scheuring, the creator, co-producer and co-writer of this TV Series.

Wentworth Miller (Michael Scofield) and Dominic Purcell (Lincoln Burrows), stated that they felt the story of Prison Break was never finished, after the show ended in season 4. They were the idealists behind bringing the show back to wrap up the story.

In December 2017 Dominic Purcell teased Season 6. Fox confirmed January 2018 that Prison Break is renewed for a 6th Season and that the Season will focus on Michael and Lincoln.

Actors Silas Weir Mitchell (Haywire) and Reggie Lee (Bill Kim) both went on to play recurring roles in the TV show Grimm (2011-2017) as the characters Monroe (Mitchell) and Sgt. Wu (Lee).

On June 1st Dominic Purcell was seriously injured during filming when an iron bar used as a set piece fell on his head, causing a broken nose and a head injury. He was immediately airlifted from Marrakesh to a Casablanca hospital.

In a promotion tour for Season 5, Robert Knepper (T-Bag) revealed, that despite having been an actor for years, a lot of fans still approach him concerning his last name. It is apparently known by a lot of people around the world, that his last name "Knepper" directly translates to "to f*ck" in Danish. Fellow Danish actors, Mads Mikkelsen and Ulrich Thomsen, have apparently played a lot of jokes on Knepper about his last name, as to which Knepper describes as "fun as hell".

There are several times throughout season 2 in which news reports can be seen on the tv and the anchors shown are Clarice Tinsley and Steve Eager of Fox 4 News in Dallas. Much of the series was filmed in the Dallas, Texas area.

Shooting began on Season 5 on April 7, 2016, and was completed on July 11, 2016.

In the first episode of the fourth season, in the first scene after the title shot, we can see a poster of the film Hancock (2008) on one of the buildings.

Michael Scofield (Wentworth Miller) is a mastermind engineer.

The initial order was for 10 episodes, but ended up being trimmed to 9. According to creator Paul T. Scheuring, one of the things they would have explored more was Sucre's storyline on the boat.

Wentworth Miller appears in the episode of House MD "Charity Case" (S08 E01) as Benjamin Byrd, a patient who suffers from a rare disease which has mental implications such as making him irrationally generous. Interestingly, Wenworth Miller's character in Prison Break, Michael Scofield, has been diagnosed with 2 psychological conditions, one of which is described as him having the constant need to help everyone around him.

When Season 5 aired, many fans were curious as to why the character Alex Mahone (William Fitchtner), who became a series regular in Season 2, was not in the series reboot. Paul confirmed that they just couldn't find a place for his character in the new story. However, Paul did hint that we might see him again in the series since the show was renewed for a season 6.

Although the show was confirmed for a season 6, no release date or cast has been announced. Paul said that, although he wants the show to continue, he doesn't want to bring it back till they have a good storyline. Since there is no rush for the series to return, we might not see the show again for a few years.

Sarah Wayne Callies, the actress who portrays Sara Tancredi, admits that she would get annoyed when people recognized her from the show and say she plays "the nurse". Since in the show she is not a nurse, she is a doctor.

Sarah Wayne Callies (Sara Tancredi) and Wentworth Miller's (Michael Scofield) birthdays are a day apart. Sarah was born June 1st and Wentworth was born June 2nd.

In the series first run (S1-S4), Michael Scofield was portrayed as a caucasian male. However, Wentworth Miller is actually bi racial (Mother is Caucasian, Father is African-American). When the series returned for a S5, Michaels profile under nationality says "Mixed"

LJ stands for Lincoln Junior.

The first trailer for Season 5 was released online on May 16, 2016.

When Robert Knepper was approached to reprise his role as T'bag for the 5th season, he said he did not want T'bag returning as the same person he was in the previous series.

Reggie Lee and Amaury Nolasco previously appeared in the first and second installments of the Fast and Furious franchise. Neal H. Moritz produces that franchise in addition to Prison Break.

Season 5 wasn't planned in the original series.

Sarah Wayne Callies (Sara Tancredi) refers to Wentworth Miller (Michael Scofield) as her TV husband.

'Sarah Wayne Callies''s character was killed in season 3 because the actress was visibly pregnant when shooting began. Sarah Tancredi was going to remain dead, but the renewal for a fourth season because of the writers' strike allowed her to return and an explanation was made up (Tancredi ran away from her kidnappers).

David "Tweener" Apolskis's death was a result of actor Lane Garrison leaving the series to finish Shooter (2007).

John Billingsley played Terrence Steadman in Season 1 but was unable to appear in Season 2 due to working on The Nine (2006). He was replaced by Jeff Perry.

In Season 2 Scofield mentions a web forum on a site That site does exist. Moreover, if you see the forum, you can actually see a thread called "The Bag's still got THE BAG", which was a message M. Scofield received from Sucre at the end of Season 2. Since then this domain was acquired by and is no longer accesible. Nevertheless, you can see the forum contents in easily, including Scofield's message.

Of the 17 people to be listed as series regulars over the show's run, the characters of Veronica Donovan and Sofia Lugo were the only ones to never be arrested. They each however were held hostage at one point.

Michael, Sucre, T-Bag and Bellick are the only characters to be incarcerated at both Fox River and Sona.

Four actors from the show later went on to star in The Walking Dead. Sarah Wayne Callie played Dr. Sara Tancredi on Prison Break and went on to play Lori Grimes on The Walking Dead. Michael Cudlitz played Rookie Corrections Officer Bob (who is murdered in season 1 of Prison Break) and went on to play Abraham Ford on The Walking Dead. Andrew Rothenberg played the psych ward nurse on Prison Break and went on to play Jim on The Walking Dead. Karl Maniken played Richard on The Walking Dead.

When Poseidon is sent to Fox River at the end of the last episode, the scene is the opening scene from season 1. You see the same footage/people and John Abruzzi in his cell too.

In Season 4 while the reunion at Michael Scofield's grave the date of his death is 11.4.2005 while in Season 5 the date of death is 11.4.2010.

The last shot of the show, with Michael and Lincoln at the park, was supposed to have a paranoid vibe according to creator Paul T. Scheuring, but ended up looking more like a happy ending.

Although Lincoln Junior and Michael Junior are first cousins, they have never had a scene together, or neither have ever mentioned each other.

After the character Sara Tancredi was killed off in Season 3, the writers already planned a new love interest for Michael in Season 4. They later scratched the idea when they decided to bring Sarah back due to fan outrage.

Season 5 contains several allusions to Homer's The Odyssey. -Odysseus, the protagonist of The Odyessy, spends seven years on an island called Ogygia. Michael, who has been missing in the seven years since his supposed death, is imprisoned in a place called Ogygia. -In one part of the story, Odysseus battles and defeats a cyclops. One of the ISIS antagonists is named Cyclops, who captures but is defeated by Lincoln and Sheba. -Odysseus's quest is to return home to his family in Ithaca. Michael's family now lives in Ithaca, New York. -The main antagonist to the season is named Poseidon. Odysseus had made an enemy of Poseidon, Greek mythology's god of water.

Although Michael was killed off at the end of season 4, they never showed his body. Leaving fans of the show to theorize for years that Michael could still be alive. The speculation finally stopped when FOX announced they were bringing the show back for a mini series. Confirming that Michael did in fact survive.

There were two endings filmed for Season 5. One was the one that aired (Michael looking at his family smiling) and one with Sara telling Michael he no longer has to look over his shoulder, with the last scene being Michael doing exactly that. This ending has a more paranoid vibe.

Before the show returned for a Season 5, Wentworth Miller (Michael Scofield) and others teased that Michael may not be the same person he was before. Since seven years had passed and he has been through a lot. However, when the show returned, Michael acted pretty much the same.

It is never confirmed whether or not Jacob survived T'bags beating.

Sara Tancredi was originally supposed to be killed off twice in the show. The first time was at the end of season one when she had her overdose. The second time was in season three when they "decapitated" her. Both times she was brought back to the series due to the characters popularity.

When Lincoln first showed Sara the picture of Michael in the first episode of season five, Sara says "Michael was sick, he was terminally sick, and, he died" however, Michael didn't die in season 4 from his sickness.

The shows seasons switch back in forth between two synopsis: season 1 was about getting out of prison, season 2 was about staying out of prison, season 3 was about getting out of prison, season 4 was about staying out of prison and season 5 was about getting out of prison.