Old Snake / Self - Celebrity Moralist (voice)
Ocelot (voice) (archive sound)
Enemy Soldiers / Vulcan Raven / Genome Soldiers (voice)
Roy Campbell (voice)
Drebin / 7th Circle - Avatar (voice)
Local Boy / MGO Soldiers (voice)
Hal 'Otacon' Emmerich (voice)
Sunny (voice)
Naomi Hunter / Little John (voice)
Raiden (voice)
Vamp (voice)
Mei Ling / Body of Armor - Satisfied Customer A (voice)
Jonathan (voice)
Ed (voice)
Rosemary (voice)
Johnny 'Akiba' Sasaki (voice)
Beast (voice)
Laughing Octopus (voice)
Raging Raven / MGO Soldiers (voice)
Crying Wolf (voice) (as Debra Wilson Skelton)
Screaming Mantis (voice)
PMC Commander / MGO Soldiers (voice)
Enemy Soldiers / MGO Soldiers (voice)
Enemy Soldiers (voice) (as Richard Horvitz)
Big Mama (EVA) / Celebrity Moralist - Host (voice)
Enemy Soldiers / MGO Soldiers / Ocen of Gossip - Co-host (voice)
Meryl Silverburgh (voice)
Enemy Soldiers / MGO Soldiers (voice) (as Erica Nann Barranco)
Enemy Soldiers / Warning Gekko / Body of Armor - Satisfied Customer B (voice) (as Kris Zimmerman Salter)
God / Missouri Crewman / MGO Soldiers (voice)
Psycho Mantis / Genome Soldiers / Ocean of Gossip - Host (voice)
Liquid Ocelot / Revolver Ocelot (voice)
The Sorrow (voice) (archive sound)
Cyborg Ninja (voice) (archive sound)
Big Boss / 7th Circle - Host (voice)
Bomb Shelter Buffet - Chef
Bomb Shelter Buffet - Rachel (as Concetta D'Agnes)
Bomb Shelter Buffet - Audience Member
Otselotovaya Kvatka - Cyborg A
Otselotovaya Kvatka - Cyborg B (as Alena Sauko)
Pieuvre Armement - Narrator (voice)
Pieuvre Armement - Swimmer A
Pieuvre Armement - Swimmer B (as Tracy Brenneman)
Pieuvre Armement - Swimmer C (as Michelle Graci)
Praying Mantis - Biker
Praying Mantis - Narrator (voice)
Ravensword - Enforcer / Body of Armor - Athlete C
Werewolf - Narrator (voice)
7th Circle - Larry
7th Circle - Melissa
Body of Armor - The Sarge
Body of Armor - Athlete A
Body of Armor - Athlete B
Body of Armor - Athlete D
Extra
Extra (as LaToya Jean Curtis)
Unnamed Soldier
Extras (as Buzz 'Todd' McEntire)
MGO Soldiers (voice)
Drebin (voice)
Liquid Ocelot (voice)
Crying Wolf (voice)
Enemy Soldiers (voice)
Vulcan Raven / The Sorrow (voice) (archive sound)
Genome Soldiers (voice) (archive sound)
Rosemary / Sunny (voice)
Little John (voice)
Little Grey (voice)
Mei Ling (voice)
Enemy Soldiers / MGO Soldiers (voice) (as Kenichiro Matsuda)
Big Mama (voice)
Major Zero (archive footage)
Gray Fox (voice) (archive sound)
Psycho Mantis (voice) (archive sound)
MGO Soldiers (voice) (as Yôko Soumi)
Otacon / Jonathan (voice)
Revolver Ocelot (voice) (archive sound)
Naomi Hunter (voice)
Ed / Beast / Psycho Mantis (voice)
Old Snake / Solidus Snake (voice)
Big Boss (voice) (as Chikao Ohtsuka)
Liquid Snake / Master Miller (voice) (archive sound) (uncredited)
Solidus Snake (voice) (archive sound) (uncredited)