The film was shot in 2014 but the release was postponed for three years. The first test screening happened in November 2014 and didn't get positive reactions. The film was originally scheduled to be released in June 2016, but the release date was pushed to July 2016, then to February 2017, August 25, 2017, and it was finally released in theaters in September 1, 2017.

This film was seven weeks away from shooting in 2004. When the British government shuttered a tax break program, the $45 million budget grew by about $17 million, and the film was shut down. The film was resurrected by Ruby Films and The Weinstein Company in 2013 and the budget has been slimmed down to $25 million.

Harvey Weinstein offered Harry Styles the role of Mattheus, but the singer turned it down due to scheduling conflicts and Matthew Morrison was cast instead.

Matthias Schoenaerts was in talks for the male lead but turned it down. He was replaced by Dane DeHaan. Schoenaerts ended up co-starring with Alicia Vikander in The Danish Girl (2015).

When Dreamworks set up the original " Tulip Fever" in 2004, they had built a massive set of the Amsterdam canals, and planted 12,000 tulips. Jude Law, Natalie Portman and Jim Broadbent were all set to star until the plug was pulled just 12 days before shooting.

In 2004, director John Madden was lining up the movie with Keira Knightley and Jude Law to star, with a script by Tom Stoppard. Once tax incentives for production in UK disappeared, the project was cancelled. Some sets had already been constructed and 12,000 tulips had to be dead-headed. Soon after that, director Peter Chelsom tried to get it made, and he didn't fare any better. Then in 2011, Tom Hooper considered it among a handful of other projects as his followup to The King's Speech (2010) before deciding on Les Misérables (2012). In July 2013, Justin Chadwick was announced as the director.

The film is set in the Netherlands with Dutch characters, but was entirely shot in UK (in Norfolk, Suffolk and at Pinewood Studios) and there's no Dutch actors in it.

Although costar Dane DeHaan descends from a mixture of European backgrounds (English, German, Dutch, Italian, and more), his last name is a Dutch term ("de Haan" means "the Rooster").

De Haan, Van Dijk and Hollander are all dutch surnames. Hollander is a less commonly used term for Dutchman.

In 2013, Alicia Vikander was cast in the lead role, but it was later reported that Holliday Grainger replaced her. This turned out to be incorrect, and it was announced that Vikander would indeed be playing the lead role and Grainger would be a supporting role.

The film was originally planned to be made in 2004, with Jude Law and Keira Knightley as lead actors and John Madden as director. However, the production was halted as a result of changes in tax rules affecting film production in the UK. Filming took place at Cobham Hall in Cobham, Kent, Norwich Cathedral, Holkham (in Norfolk), Tilbury, (in Essex), Kentwell Hall (in Suffolk) and at Pinewood Studios on various dates throughout June and July in 2014. The London-based Welsh portrait artist Jamie Routley did the original portraits that are seen in the film.

The film cast includes three Oscar winners: Judi Dench, Alicia Vikander and Christoph Waltz.

The actor of Dr. Sorgh is called Tom Hollander. Ironically, Hollander is a dutch term for Dutchmen. This is, however, not completely valid. 'Hollander' refers to someone who comes from Holland. Holland isn't, in contradiction to what many people think, The Netherlands. In fact, only two of the twelve provinces in The Netherlands are called Holland: Noord-Holland (North-Holland) and Zuid-Holland (South-Holland). In the Golden Age of The Netherlands, Noord-Holland and Zuid-Holland were the most wealthy provinces in The Netherlands, because the most important cities are situated in those provinces (think about Amsterdam, Leiden, The Hague). Because the most important cities were situated in the Holland-provinces, people started to call The Netherlands 'Holland', because they only went to the Holland-provinces.

Cressida Bonas' movie debut.

Dane Dehaan and Cara Delevingne have also starred together in Valerian and the city of a thousand planets.

Along with producers Alison Owen and Harvey Weinstein, director Justin Chadwick decided to cast Alicia Vikander for the female lead in 2013.

Jack O'Connell and Holliday Grainger starred together in short film Home (2016).

Judi Dench and Christoph Waltz have both starred in Bond movies, Dench in all Pierce Brosnan and Daniel Craig Bond films [to date, October 2017], and Waltz in Spectre (2015), with this Bond movie being the only one in which they both appear, but share no scenes, with Dench appearing only in flashback, as well as also pictured in the opening titles.