In Season 3: Episode 3, Diana (Marsha Thomason) has to speak in an English accent for an undercover assignment. In real life, Marsha Thomason is from Manchester, England.

Charles Dickens references: In the episode "Upper West Side story", where the class is studying "A Tale of Two Cities," Mozzie introduces himself to Evan as Professor Magwitch. Mozzie also often uses the alias "Havisham." Both are names of characters in Great Expectations.

In the season finale of season 1, Mozzie states "I don't wanna end my days in some underground prison adopting cockroaches as pets". Willie Garson's character Stanley Nussbaum in Fortress 2 (2000) was a mentally challenged inmate who had a cockroach for a pet.

In Season Two, the decreased presence of the character Elizabeth Burke, and conspicuous green-screen scenes, was due to the pregnancy of her actress, Tiffani Thiessen.

In the episode White Collar: Bottlenecked (2010) Peter calls Matthew Keller the "Bizarro Neal" which is a reference to a character Tim DeKay played in the comedy series Seinfeld (1989) where he played Kevin in the episode Seinfeld: The Bizarro Jerry (1996), which was a reference to "Bizarro" characters in comic books.

Inspired by the exploits of Frank Abagnale Jr who was once a counterfeiter and confidence trickster who ended up working for the FBI

One of Neal's aliases is Nick Halden. This is a reference to the name of Tony Curtis' character in the movie "Operation Petticoat"

Neal Caffrey is portrayed as womanizer who, because of his good looks, is able to charm and bed many different women throughout the series. In real life, his actor Matt Bomer is married to another man and has three children.

Tim DeKay is a graduate of Le Moyne College. In episode 12, White Collar: Bottlenecked (2010) DeKay's character Peter is seen holding a Le Moyne sweater.

In Season 4 Alex is staying at the Athenian hotel on 10th Avenue. This was actually filmed inside SIXTY LES, a hotel near the corner of 1st and 1st. There is an art connection here too as the pool at SIXTY LES has a portrait of Andy Warhol in the bottom!

Two year before this series, Matt Bomer played a man wrongly accused for bombing a museum pursued by the FBI as a criminal in the short-lived series, Traveler (2007). Here, he plays a man who robs museums and was caught by the FBI.

Tiffani Thiessen's character's name "Elizabeth Burke" is suspiciously similar to "Elizabeth Berkley", one of her costars in Saved by the Bell (1989-1993)

In the episode Stealing Home, it took Bomer over 100 times to pull off the impossible pool shot.

In Season 5, Diana decides to get pregnant via sperm donor and be a single mother. In real life, Marsha Thomason was pregnant by her husband, Craig Sykes. The show decided to write in Thomason's pregnancy instead of making Diana disappear.

In White Collar: Stealing Home (2012) Neal reveals to June and Mozzie that he grew up in St. Louis, and that he was already a pool shark by age 9.

Season 4 makes reference to being in Cabo Verde Islands, but it was filmed on Puerto Rico.