Jason Antoon and Seana Kofoed, who play Ernie and Medical Examiner Chase, respectively, are husband and wife off-screen.
May 2, 2021, CBS announced the official name of the series would be NCIS: Hawai'i (with the okina or glottal stop between the two I's), reflecting the state's name in the Hawaiian language and the official name for the Big Island of Hawai'i.
Enver Gjokaj [Navy Captain Joe Milius] appeared as the character, Marku, in Hawaii Five-0, which is part of the same 'TV Universe' as NCIS.
This show uses the same Honolulu PD vehicles as Hawaii Five-0.
This is the first show in the NCIS series that doesn't have a 'back-door' episode connecting it to either of its predecessors.