Jenny mentions that Brad Alexander is an unsuitable date since he gave six girls from Nightingale an STD. Nightingale is the Nightingale-Bamford school, the school on which Constance-Billard was based.
Serena van der Woodsen:
You loved me?
Nate Archibald: Of course, I did. Serena, you're the most beautiful, amazing, alive person I've ever known.