A dead man is found handcuffed to a bed in his own home; as Korsak's retirement party approaches, everyone makes a video to say goodbye; the group says farewell and plans for their next adventure. Series Finale.
An under-cover cop is killed by a drug ring. They then attack police HQ to retrieve a crucial piece of evidence found by Rizzoli at the crime scene. Rizzoli, Dr. Isles and others are trapped inside the HQ. A shoot-out ultimately ensues.
The death of a former drug addict is found to be connected to Rizzoli and the person who set fire to her apartment, hacked her financial accounts and threatens her and those close to her.
Maura is kidnapped and Jane and the team do everything they can to find her before she is harmed. While abducted, Maura discovers a conspiracy that puts a target on Jane's back.
When a warehouse fire kills a firefighter, Jane and Maura must investigate whether it was arson or an accident. But the investigation hits a snag when a hit-and-run leaves someone in the hospital.
Jailed Hoyt is dying of cancer and Randall, his fellow inmate, is murdered. Hoyt conveys confusing images to Rizzoli who then attempts to connect deaths of Randall and of the four Wilsons in 2005, to Hoyt. Rizzoli's birthday is celebrated.
In the 100th episode of the series, Jane risks her safety to go undercover in a county jail in an effort to acquire details from a woman believed to be in some way involved in a brutal double-homicide.