Goofs

The toilet mirror reappears intact after being repeatedly smashed during the fight sequence.

When Elisabeth is first checking out Sue after transforming back after Sue's first 7 days, both women are lying naked in the lab. However, in one shot, Elisabeth's arm is in a white-toweling dressing gown as she strokes back Sue's hair, but in the next shot, she is naked again.

When Sue removes the picture of Elisabeth, as she shoves it through the hallway, the crack in the glass is gone.

The coffee table reappears after being shattered in the fight sequence.

Right before Sue gets the Matrix food bag, it is already on the floor next to Elisabeth. She then goes to the bathroom cabinet to retrieve it.

The hidden room Sue builds is impossible; No modern building has an unused, room-sized empty space in the wall cavity. Especially not in a contemporary high-rise apartment building, like Elizabeth's. In reality, the only way to construct such a room would be to sacrifice space in one or more existing rooms (which isn't what's depicted; Sue just hammers through the bathroom wall, to discover a large, dark, unused cavity in the wall-space).

When Elisabeth calls the number on the USB stick, a British-style double ring pattern is heard instead of the single ring that would be heard when calling a US number.

She is provided with easily 5-10ml of activator she is only to use once but a 1ml syringe. Seems a waste of an important medication.

According to the plot, the substance divides existing DNA and duplicates the same person. However Elisabeth has green/hazel eyes but Sue has blue eyes.

Snow is shown falling on Elisabeth's star on the Hollywood Walk of Fame. The film is set in 2022 (as shown by the May 2022 calendar at about 45 mins), so Elisabeth was born in 1972, 10 years after Los Angeles had its last snowfall.

With her last transformation Elisabeth turns out to be a deformed hunchback who looks at least 90 years old, but yet she can run long distances, run down and up stairs, and carry an unconscious body without a problem. It's possible that she is actually still only 50 but just looks much older, which is why she can do all these things.

As Liz is so obsessed with conforming to the beauty standard, it makes no sense for her to go on stage as the monstrosity she becomes.

However, not only is her mind in turmoil at this point, but the film is an extreme satire, and not meant to be taken entirely literally.

At about 18 mins, the casting call says "Auditions at the studio this Friday" but never mentions which studio, let alone its address or any contact info.

Several times a large billboard is shown just in front of the window of Elisabeth's apartment, even though judging from the city seen below, it's way too high for a typical billboard.

There's no way Liz could miss part of the preparation for the New Year's show and then just walk straight to the stage from the outside without meeting anyone who's been looking for her, or anyone else involved with the show for that matter.

Its unlikely that Sue would be able to sign up for a modeling gig without any issues if she doesn't have any paperwork or identification that says she exists. At the very least, the showrunners would need to see some form of legitimate ID matching her name before letting this complete stranger into this huge role.

Sue and Elisabeth seem to have two different minds; they seem to share no consciousness. After MonstroElisaSue is birthed, it and Sue are the same person with shared memories and self.

Twice someone in a television studio is counting down to going on air, and they say each number. In real life, the person would merely mouth "two" and "one", not say them aloud.

During the fight sequence, when Sue chases Elizabeth toward the bathroom, it can be seen that she is wearing trainers as she runs. However, Sue is meant to be barefoot for the entire scene.