According to
Fred Armisen and
Carrie Brownstein, the Women and Women First Bookstore scenes are actually shot at the very same non-profit bookstore that inspired the characters. The store, called In Other Words, was filmed mostly as-is, without any additional set dressing. In Other Words eventually ended their relationship with Portlandia for two stated reasons: the production's fees to close the store for filming didn't make up for sales lost on a given day, and the characters of Toni and Candace were seen by the staff as transphobic.