The close-ups of of a young Gus Lobel (Clint Eastwood) in a flashback were from footage taken from the Eastwood movie Firefox (1982).

Clint Eastwood said about himself acting in this movie about aging in an interview: "You get to a certain age, you're just glad to be there. You have to be a realist so you try to look for roles that are within the age range you are in. It would be kind of ridiculous if I wanted to play a thirty-five-year-old guy. I've enjoyed the journey to this stage and I intend to enjoy the rest of the journey."

Sandra Bullock, Amy Adams, and Reese Witherspoon were considered for the role of Mickey in that particular order. Bullock declined due to scheduling conflicts, so the role was offered to Adams.

Clint Eastwood originally hinted that Gran Torino (2008) would be his final acting role (although he would continue to direct). The filmmakers got him to change his mind and come out of acting retirement to star in this movie.

Baseball coordinator Aimee McDaniel said of working on this movie: "We worked with Amy Adams for four or five days, and by the end of that time, she looked like she'd been catching baseballs her whole life. To have an actress of that caliber just throw herself into something like that made my job easy. And the rest of the cast was equally devoted."

Clint Eastwood's first major acting role in a movie he did not direct for nineteen years, the last having been In the Line of Fire (1993).

Debut movie as director for Robert Lorenz who has been a long time collaborator of Clint Eastwood in various areas such as producing and assistant directing.

The scenes shot at Atlanta's Ted Turner Field were achieved just ahead of the Atlanta Braves' baseball season home opener. Some of the players were on the field warming up while the cast and crew were shooting in another part of the stadium.

Appearing in this movie is Scott Eastwood, son of Clint Eastwood. Its the fourth movie of his father's in which he's appeared.

During this movie, Phillip Sanderson (Matthew Lillard) refers to the scouted prospect; Bo Gentry (Joe Massingill), as having "all five tools". The five tools in baseball refer to a players' ability to hit the ball for average, and for power, be talented defensively, have a good throwing arm, and have a considerable amount of speed. Judging on the few scenes where Bo runs, he's not exceptionally fast, and based on his large round stocky build, it is highly unlikely that he is very fast. Perhaps the writers inserted this quote in order to display Lillard's character of having ignorance to baseball and only basing his facts off of a computer without watching him play, especially considering this is actually a very large part of the plot.

In an interview, Clint Eastwood said of what it was like being directed as an actor by Robert Lorenz): It was horrible, I had to listen to everything he said. Robert and I have worked together for almost twenty years now. We've talked about him directing over the years, so when he showed me this script, I thought it was a perfect opportunity. I had no doubt he'd do a terrific job, and he absolutely did."

Screenwriter Randy Brown said of central character Gus Lobel (Clint Eastwood) that Gus is "a crotchety old guy who was kind of being phased out by the young blood and the new technology. It's happening every day in our country, and not just in baseball. I wondered how that must make someone feel, being pushed out to make room for someone else climbing the ladder."

According to the production notes, "To ensure a sense of realism on the playing field, Lorenz also hired baseball coordinator Aimee McDaniel to help organize, choreograph and rehearse the athletes, and train the actors to look like players, even Amy Adams". Producer and director Robert Lorenz has said: "Aimee came to Georgia and basically recruited all the different teams and help we needed. She did a great job, so that was one aspect of production I didn't have to worry about. Everybody knew what they were doing and they were all good players, or at least looked like they were."

Producer and director Robert Lorenz, according to the DVD short documentary, personally cast Amy Adams in the movie.

The movie's crew contained quite a few regular collaborators from Clint Eastwood's "Malpaso Company". These included producer and director Robert Lorenz, director of photography Tom Stern, production designer James J. Murakami, costume designer Deborah Hopper, and location manager Patrick Mignano.

Producer and director Robert Lorenz has said of this movie: "It was just a matter of finding the right project at the right time", Lorenz states. "I felt the story had broad appeal, a lot of humor, with really great characters and interesting relationships, and I could easily visualize what I would do with it as I read it. The fact that it had a great role for Clint Eastwood and he was interested in playing it was way more than I could have hoped for."

Justin Timberlake drew on his own personal experiences "calling" baseball games as a kid to play his character who was a baseball scout in this movie.

According to show-business trade paper "Variety", "the picture was lensed primarily in Georgia, with extensive access to Atlanta's 'Ted Turner' Field".

Amy Adams has said of working with Clint Eastwood: "Working with Clint was amazing. He is truly a legend, so to share the screen with him was an honor."

On the subject of baseball scouts, Clint Eastwood said in an interview: "These guys have a tremendous responsibility, because they're often signing players who are seventeen, eighteen-years-old, to major league contracts with a lot of money dropped in their laps. Scouts have to be part psychologist as well as have an eye for the game, so they can be sure they're not betting on the wrong horse."

Location manager Patrick Mignano was instrumental in securing one of the production's greatest coups by being about to conduct filming at the Atlanta Braves' Ted Turner Field in Atlanta.

Clint Eastwood became available for this movie when the planned remake of A Star Is Born (1954) was put into turnaround when Beyoncé became pregnant.

"Trouble With the Curve" was in theatrical release when Clint Eastwood spoke at the 2012 Republican National Convention. The speech is best known for the "Barack Obama's Empty Chair" speech.

The fictional Swannanoa High School was located in Dunwoody, just north of Atlanta. Additional "away" games were shot in Jasper, where Jasper City Park became this movie's Arden High School, and a championship game was played at Young Harris College, just a few miles from the North Carolina border in North Georgia. The production also filmed at a facility at Georgia Tech, and filmed a minor league game at Luther Williams Field in Macon, Georgia.

During the dinner scene between Mickey and Greg, she overhears a conversation about Jair Jurrjens pitching a no-hitter. Jurrjens, a native of Curacao, pitched for the Braves from 2008-2012 and originally reached the majors with the Detroit Tigers.

Clint Eastwood's first acting role in a movie he did not direct for seventeen years, the last having been his cameo in Casper (1995).

Turner Field, featured throughout the movie as the home of the Braves and headquarters for their front office, is no longer used by the Braves. In 2017, the Braves moved to SunTrust Park northwest of downtown Atlanta. The facility has been purchased by Georgia State University and will be the home of their football team.

According to the DVD short featurette, this movie was predominantly shot in sequence as much as possible.

John Goodman was cast in this baseball movie having previously played baseball legend Babe Ruth in The Babe (1992).

Clint Eastwood's first acting role in a movie for four years, the last having been Gran Torino (2008).

In Bo Gentry's (Joe Massingill's) last championship game before being drafted, the game purportedly takes place at Zeb B. Vance Field, which is the playing field for Zebulon B. Vance High School in Charlotte, North Carolina.

Debut produced screenplay of Randy Brown.

This movie, a baseball movie, is the just the second sports movie in which Clint Eastwood has acted. The first, about boxing, was Million Dollar Baby (2004). He also directed and produced the movie Invictus (2009), about the 1995 Rugby World Cup.

Debut theatrical movie of Joe Massingill (Bo Gentry).

The route of the cross-country road went from Georgia to North Carolina.

Though Clint Eastwood did not direct this movie, nor composed the music as he has done on several his own movies, Eastwood was still a producer, an actor, and the top-billed lead star.

Contrary to the finale of this movie, many baseball players have vast potential despite their "trouble with the curve". That's where the hitting coaches come in and work with them. A pitcher is less valuable than a versatile utility player.

Producer and director Robert Lorenz brought the screenplay by Randy Brown to the attention of producer Michele Weisler.