The series was created by Camilo Cano and Juana Uribe who are both closely tied with Pablo Escobar. Camilo Cano is the son of Guillermo Cano who was the publisher of newspaper El Espectador and who was murdered by Escobar in December 1986. Juana Uribe is the vice president of Caracol TV and also the series' producer. She is the daughter to Maruja Pachón who was kidnapped by Pablo Escobar on 7 November 1990 and later released. Juana is also the niece to presidential candidate Luis Carlos Galán who was killed by Escobar in August 1989.
The series is set in the mid-1980s but all the $20 and $100 dollar bills shown were introduced in the 2000s.