Co-creator and director John Fawcett has cited Memento (2000) as a major inspiration for Orphan Black.
In season 1, Cosima confidently refers to the clone experiment being "double blind." However, this is a factual mistake. A double blind experiment is designed such that neither the participants nor the investigators know which participants belong to the test group(s) versus which participants belong to the control group. If this were a double blind experiment, Cosima would have no way of knowing unless she had designed the experiment herself. She would also know that a double blind design requires a control group, whose existence she would likely seek.
More likely is that the experiment is single blind, where the participants do not know the group(s) to which they belong, but the investigators do know. However, once again, Cosima would have no way of knowing this information about the study design unless she were herself an investigator. As a graduate student scientist, realistically, she would at least know the difference between a double blind and single blind design.