- Mild
- At one point, a girl says "and for me it would be "'F' Thor, marry Iron Man and kill Hulk."
- It has more profane language than all previous Spider-Man films combined.
- "Ass" and similar words are used.
- "Suck," "god," "crap," "penis," "hell," "damn," "ass," "bastard," "asshole," "shit," on-screen use of the middle finger, and two separate uses of "fuck" that were bleeped in-universe and unfinished towards the end respectively.
- "Crap," "hell," "damn," "ass," "bastard," "penis," "asshole," & "shit." There is one bleeped use of the f-word and one notable cutoff of the same word at the last scene just before the credits.
- One incomplete use of the f-word; other minor profanities, used infrequently, like "shit," "damn," "bastard," "bitch."
- Middle finger, as an insult, is used once.
- After the end of movie, Aunt May walks in the room and she saw Peter is the real superhero 'Spider-Man'. And she says "What the Fu-!" at the end before the credits roll.