HBO originally passed on the pilot. HBO later picked up the series after James Gandolfini and Steven Zaillian agreed to make a mini-series instead of an open-ended series. Gandolfini died suddenly a month later.
Robert De Niro stepped in to take over the role originally played by the late James Gandolfini. When scheduling issues forced De Niro to drop out, John Turturro took the role.
Peyman Moaadi and Poorna Jagannathan, who play Riz Ahmed's parents in the show, in real life are only 10 years older than Riz Ahmed.
"The Night Of" is based on a British TV series that ran from 2008-09 called "Criminal Justice." This can be confirmed by credit that is displayed after each episode.
John Stone's problems with his feet seem to reflect Naz's situations; the worse Naz's situation gets, the worse Stone's condition gets.
Nicolas Turturro, John Turturro's brother, appears as the detective interviewing the female arresting officer at the beginning of episode two.
Riz Ahmed spent some time researching aspects of his role at New York's notorious Rikers Island prison.
Michael Kenneth Williams (Freddy) and J.D. Williams (Trevor) both had roles in "The Wire" as Bodie Broadus and Omar Little.
Aida Turturro, who played the role of Janice Soprano in The Sopranos, and Max Casella, who played the role of Benny Fazio in The Sopranos, appear in the episode titled "The Art of War".
Both Michael Kenneth Williams and Paul Sparks starred alongside each other in Boardwalk Empire. Steve Buscemi who is also the star of Boardwalk Empire has a brother named Michael Buscemi who has a small cameo in The Night Of in an episode as a member of the eczema support group.
Defence lawyer John Stone (John Turturro) asks his son to choose Denzel (Washington) for his school job. Denzel Washington and John Turturro both starred in Spike Lee's film "Mo' Better Blues".
The UK's Criminal Justice (2008) season one stars actor Ben Whishaw; The Night Of is based upon this original series. Michael Braun and Bill Camp, who are in The Night Of, co-star with Ben Whishaw in the 2016 Broadway revival of Arthur Miller's The Crucible.
Features two actors who previously played Murry Wilson, father of Carl, Dennis, and Brian Wilson of the Beach Boys. Kevin Dunn played Murry Wilson in "The Beach Boys: An American Family" (2000) and Bill Camp played him in "Love & Mercy" (2014).
The series reunites three actors who appeared in Quiz Show (1994): 'John Turturro, Jack Gilpin and Ben Shenkman. They didn't share scenes in that movie but in the series Turturro appears with both actors.
Kevin Dunn and Adam LeFevre previously appeared in The Bonfire of the Vanities (1990).