In the film, Jason Bateman and Rachel McAdams makes a joke about child actors not amounting to much. Bateman was a child actor famous for his role on The Hogan Family.
Prior to filming, the cast members had their own "game night" so they could get to know one another and prepare for the film. They played Clue and Joking Hazard.
Jason Bateman was originally set to direct the film, but Daley and Goldstein would only work on a rewrite of the script if they could also direct.
In addition to referring Quentin Tarantino's films, Pulp Fiction (1994) and Django: Unchained (2012), the movie modeled a scene using Tarantino's signature one-take continuous long shot.
Ryan (Billy Magnussen) keeps referencing an underground fight club. During a guessing game, Max (Jason Bateman) has to get Annie and his friends to guess the actor Ed Norton. Edward Norton was one of the main stars of Fight Club (1999).
Director John Francis Daley played Carter in the film. In Horrible Bosses (2011), he played a character also named Carter.
The character of Gary Kingsbury was named after John Francis Daley's wife, Corinne Kingsbury.
The opening title sequence shows game pieces from many classic board games including Battleship. Battleship is referenced later on as a game Max and Brooks played as kids. Jesse Plemons who plays Garry had a role in the movie Battleship (2012).
Jesse Plemons and Billy Magnussen both appeared in an episode of Black Mirror (2011) in its fourth season called "U.S.S Callister."
This was the second film Jason Bateman and Rachel McAdams starred in together. The first was State of Play (2009).
One of the filming locations was RiRa Irish Pub, 1010 Peachtree Street. NE, Atlanta, GA on April 4, 2017.
In keeping with the theme of games referenced in the film, there is a subtle reference to a classic 1970s board game. When the group first enter Donald Anderton's (Danny Huston) lavish home, the painting "Old Man with a Gold Chain" by Rembrandt can be seen hanging on the wall. This is one of the paintings from the Art Institute of Chicago which is featured in the board game Masterpiece.
The film contains references to Iron Man and the Incredible Hulk films in the Marvel Cinematic Universe. Rachel McAdams, who stars in this film, had actually previously appeared in the MCU in a role in Doctor Strange.
The airport truck (with the conveyor belt) is a clear reference to the Arrested Development stair car, a show in which Bateman also starred.
Kyle Chandler and Jesse Plemons both starred on the TV show Friday Night Lights (2006).
The film was promoted on February 12, 2018 in Atlanta, Georgia by Micaela Dee and her fellow "Murder Mystery Dinner Theater" players.
Both Jesse Plemons and Kyle Chandler have starred in Grey's Anatomy. Plemons played Jake Burton in season two, a patient with advanced craniodiaphyseal dysplasia. Chandler starred as Dylan Young, from the bomb squad in season two.
This was the second film Rachel McAdams and Michael Cyril Creighton appeared in together. The first was Spotlight (2015).
The movie makes references to two Marvel Comics properties, Iron Man and Hulk. Rachel McAdams starred in a film from the Marvel Cinematic Universe, Doctor Strange (2016).