During Dr. Leland's court appearance for her speeding violation, Lester mentions she was driving a 3-series with the N54 twin-turbo inline 6 (engine). This is an actual BMW car and engine combination, and the internal company code used to identify this particular engine really is "N54". This means that despite his simple nature, Lester is a car aficionado and likely very tech savvy for even knowing this information.
A southern route from Los Angeles to Bridgehampton would take Interstate 20 through the movie' filming location in Ouachita Parish, Louisiana. However, Lisa would have no reason to be on a two-lane country road unless she was already looking for something off the Interstate.