Episode titles during the first season were taken from song titles from the 1960s. Episode titles in the second season were taken from the Beatles' "White Album".

"Sadie" is one of Manson's most loyal followers in the show. In real life, Sadie was Susan Atkins' nickname given to her by Manson. She became a born-again Christian in the mid-70's, renounced Manson, and died of a brain tumor while still incarcerated in 2009.

On October 1st NBC announced that Aquarius had been cancelled after 2 seasons.

Charles Manson's favorite album was the Beatles 'White Album'.

"Healter Skelter" is written on the fridge at the LaBianca murder house. Helter Skelter was a song on the Beatles 'White Album'.

Debra Tate, sister of Sharon Tate, urged a boycott of this show. She said the graphic depictions of the murders were "extremely insensitive," and that movies and television need to change the way they portray real-life murders. She attempted to schedule a meeting with NBC to discuss the matter, but was "completely ignored."

Vincent Bugliosi, who worked extensively on the Manson case, wrote a book about Manson and the family called Helter Skelter.

Both Clair Holt and Makayla McManus were also on The Vampire Diaries.

Manson names the kidnapped baby Valentine Michael. It's a reference to the rumor that Manson was trying to emulate the protagonist in Robert Heinlen's novel Stranger in A Strange Land, who was named Valentine Michael Smith. This was debunked in the late 1980s, when Manson was asked about the rumor and he said he'd never heard of it.