Male Protagonist #1 / Oedon Chapel Dweller / Critically Ill Man / Laurence (voice)
Male Protagonist #2 / Laurence / Yharnamite (M1) / Messengers (voice) (as Joe Simms)
Male Protagonist #3 / Patches the Spider (voice)
Male Protagonist #4 (voice) (as Andy Tiernan)
Male Protagonist #5 / Mob in Wheelchair (voice)
Female Protagonist #1 / Imposter Doctor / Sister Adella / Vicar Amelia (voice)
Female Protagonist #2 / Lonely Old Dear (voice)
Female Protagonist #3 (voice)
The Plain Doll (voice)
Old Hunter Gehrman (voice)
Annalise, Vileblood Queen / Doctor Iosefka (voice)
Blood Minister / Transformed Man (voice)
Provost Willem / Micolash - Host of the Nightmare / Yharnamite (M2) (voice)
Micolash - Host of the Nightmare / Mob A (voice)
Narrow Minded Man (voice)
Arianna - Women of Pleasure / Yharnamite (F2) (voice)
Girl (voice)
Older Sister (voice)
Father Gascoigne (voice)
Retired Hunter Djura / Gatekeeper (voice)
Vileblood Hunter Alfred (voice)
Hunter of Hunters / Yharnamite (F1) (voice)
Mob B / Messengers (voice)
Mob Woman (voice)
Ludwig's hunters
Santa Adeline (voice)
Iosefka (voice)