The idea for the show was pitched to the studio as a 4 volume graphic novel released through dark horse comics.
The show is set 600 years in the future, as established in episode 3.10.
From Season 2 onward, a line of dialogue from each episode serves as that episode's title.
The cast is credited at the beginning of each episode according to their "number."
Jodelle Ferland's character uses the ships vents to move around. Jodelle is the voice of the Little Sisters in Bioshock 2, who also uses vents to move around.