The film had three thousand set-ups, thirteen helicopters, six pregnancies, five hiatuses, four weeks of aerial photography, three continents, two winters and one broken ankle.

Tom Cruise trained for an entire year to perform the HALO (High Altitude Low Opening) stunt in this film.

While filming, Tom Cruise fractured his ankle in a stunt where he leaped from a building. Production was halted for seven weeks, but the July 2018 release date was kept.

This film was green-lit several days before the release of Mission: Impossible - Rogue Nation (2015).

Tom Cruise and Ving Rhames are the only actors to appear in all six "Mission: Impossible" films. Simon Pegg has been in every movie since Mission: Impossible III (2006).

Jeremy Renner was not in this film, due to his commitment to the Marvel Cinematic Universe.

At 2 hours and 27 minutes, this is the longest "Mission: Impossible" film to date.

Christopher McQuarrie was the first director in the franchise to direct more than one film.

Solomon Lane is the first villain in the franchise to appear in two films.

Rebecca Ferguson was the first actress in the franchise to appear twice in a leading role.

Rebecca Ferguson was pregnant while filming this movie. She was about seven months pregnant when filming was completed.

In June 2017, Tom Cruise, Michelle Monaghan and Simon Pegg arrived in New Zealand to begin filming scenes. It was Cruise's first time in the country since filming The Last Samurai (2003).

Henry Cavill replaced Tom Cruise for The Man from U.N.C.L.E. (2015).

In August 2017, Tom Cruise suffered an injury while filming a stunt jumping from one building to another. He was able to grab onto the other building thanks to a harness strapped onto him and his history of performing his own stunts for action films, but his ankle fractured upon the impact of the jump. Cruise then got up and attempted to run it off, which was presumably what the scene called for, before he and the crew decided to stop filming. Shooting was delayed for eight weeks following the injury, but the footage of the stunt used in the film's trailers just so happened to be the actual injury.

Simon Pegg got in such good shape while training in the gym for his action scenes that he got eight-pack abs for the first time in 25 years even though it wasn't required for his role at all. The actor is not an action star or known for his body and was teased on set by co-stars Tom Cruise and Henry Cavill, who actually are action stars and regularly show their eight-pack abs in films. They nick-named Pegg 'Eight-Pack Peggles' due to his new found abs. Cruise said, "Six-Pack Peggles I call him! He had an amazing eight-pack going on. He's almost like Eight-Pack Peggles." Pegg responded to the good-natured teasing saying, "To be fair it was a six-pack, it wasn't quite an eight-pack. I think one morning, after training, my abs made an appearance for the first time since I was 23. You have to be in shape to do these movies and I put my mind to it. It's nice to know that I can still show out if I need to. My wife appreciates it!"

Alec Baldwin found his fight scene with Henry Cavill particularly challenging to execute because of Cavill's sheer size and musculature. Baldwin's comment about the encounter, "I had to do a fight scene with Henry Cavill and Henry Cavill, as everyone knows, plays Superman. Well, he really is Superman. The guy's body is like it's made of marble. When you do fight scenes, you throw these punches, you tussle with the guy and you move him around... he's pretty hard to move around and his shoulders are so big that when they shot my close-up over his shoulder, I asked, could you bend down please because your shoulders are in the way of the shot. He's just so big! But I had a ball working with him."

Tom Cruise said in an interview that if Mission: Impossible - Fallout (2018) does well, they'll make more. For now, he'll still create them, but directors/writers may change.

This is Michelle Monaghan's third appearance in the "Mission: Impossible" franchise. She first appeared in Mission: Impossible III (2006) and returned in a uncredited cameo in Mission: Impossible - Ghost Protocol (2011). She was absent from Mission: Impossible - Rogue Nation (2015).

Due to additional safety equipment and challenges with the weather in November, the production company sought permission for about 800 landings by helicopter on the cliff Preikestolen in Norway. A stunt is supposed to be performed there at almost 2000 feet (600 meters) above the fjord below.

This was the first "Mission: Impossible" film to be released in 3-D.

The production wrapped after 161 shooting days.

Henry Cavill revealed that even being Superman didn't prepare him for the extreme stunts of this film. Cavill noted that his training for Superman is geared more towards body-sculpting for shirtless scenes while stunts require more functional training. He added, "It is a very different kind of preparation for this. For Superman, it is a lot of getting the body looking a certain way when inevitably Superman gets his kit off. But for this, it is not about that. It is about prepping for the stunts, rehearsing the stunts, making sure everything is finessed and going right and I love that. It was a very different approach and I enjoyed it enormously."

Henry Cavill is the second lead actor from The Tudors (2007) to have appeared in the "Mission: Impossible" franchise. The first was Jonathan Rhys Meyers, who appeared in Mission: Impossible III (2006).

This is the second "Mission: Impossible" film for Rebecca Ferguson.

Alix Bénézech is the third French actress to play in the saga after Emmanuelle Béart in Mission: Impossible (1996) and Léa Seydoux in Mission: Impossible - Ghost Protocol (2011).

Jeremy Renner had to drop out of this project to appear in Untitled Avengers Movie (2019), based on Marvel Comics. Henry Cavill also plays a superhero character, Superman, from DC Comics.

This is the sixth and (as of its release) final film in the series.

The second "Mission: Impossible" movie to have IMAX-formatted sections.

Filming lasted almost an entire year as production was halted for a few months due to Tom Cruise' broken ankle.

Henry Cavill also played a CIA operative in The Man from U.N.C.L.E. (2015).