According to lead actor John Krasinski, the CIA Headquarters in Langley (VA) granted the production access to parts of the complex that had never been filmed before.
Unlike most previous installments in the Jack Ryan film series, the show is not based on any of Tom Clancy's novels. John Krasinski described the plot as a "ripped from the headlines" story based on current geopolitics.
Production for season two began in mid-2018 in Europe, South America, and the United States. Shooting locations included Bogotá, Colombia (standing in for Venezuela), London, Moscow and New York.
Season 2 was confirmed before season 1 even aired.
The technical advisor's MCADS drop in season 2 is very authentic as the vessels are routinely destroyed, lost at sea, or crippled due to rigging and other system failures.