In an attempt to take over the world, Dr. Calamitous (Tim Curry) has kidnapped the the greatest spy and movie star in the world - Jet Fusion (Dave Fouquette). Luckily, Jimmy Neutron (Debi Derryberry) is here to stop him. The players will have access to high-tech gadgets and spy vehicles, such as the Pulse Light Ray, Gust Buster Fan, Grappling Hook, Neutron Duplicator, Magnetic Tuner, Jimmy Bot, Trajectory, and many others. Additional features include original voices from the television show, five unique worlds, and sixteen levels. Also available for the Nintendo GameCube.
—Paul Gerard Kennedy