(2018) Sterling K. Brown's Golden Globe award for Best Actor in this drama TV series made him the first black man to win this category in the ceremony's 75-year history.

Mandy Moore is the youngest actor in the main cast despite playing the mother of Randall, Kate and Kevin.

Almost completely broke when she landed the role of Kate on the series, Chrissy Metz only had 81 cents in her bank account when she auditioned for the series.

The same house is used in an outdoor shot of Kate's home as is for Mitch and Cam's home in Modern Family (2009).

When Rebecca and Randall say to each other "I love you", "I love you more", "I love you most", this is a reference to Tangled (2010), in which Mandy Moore starred.

Mandy Moore won her role after an audition suggested by writer Dan Fogelman, whom she knew from working on Tangled (2010).

Randall and Beth met in college. Sterling K. Brown and Susan Kelechi Watson also met in college; they attended the NYU's Tisch School of Arts together.

Caitlin Thompson, who plays Madison, is the wife of Dan Fogelman, the creator of the show.

In Season 1 of This Is Us (2016), Chris Sullivan hides the show's People's Choice Award in scenes at Randall's house. As seen on The IMDb Show (2017).

Chrissy Metz actually sings in the series.

Sterling K. Brown and Susan Kelechi Watson both also appeared on Third Watch (1999) and they have known each other since grad school.

Sterling K. Brown, Denis O'Hare, Chrissy Metz and Alexandra Breckenridge have all appeared in TV shows produced by Ryan Murphy. Brown was in American Crime Story (2016). O'Hare, Metz and Breckenridge were in American Horror Story (2011).

Ken Olin (Executive Producer) and Timothy Busfield (Director) worked together on Thirtysomething (1987).

Sterling K. Brown and Ryan Michelle Bathe (who portrays Yvette) are married in real life.

The same art work representing a drawing of a man, appears in Grace and Frankie (2015) in the den of Robert Hanson (portrayed by Martin Sheen) as does in the home of Beth & Randall.

The wall art hanging in Kate's living room is the same as a wall hanging in Jules' living room in Cougar Town (2009).

Ryan Michelle Bathe auditioned for the role of Beth

Milo Ventimiglia was nominated for the 2018 Emmy Award in the Lead Actor in a Drama Series category for his role as Jack Pearson in This Is Us (2016), but lost to Matthew Rhys from The Americans (2013).

Sterling K. Brown was nominated for the 2018 Emmy Award in the Lead Actor in a Drama Series category for his role as Randall Pearson in This Is Us (2016), but lost to Matthew Rhys from The Americans (2013).

Sylvester Stallone appears in the second season as himself and Kate tells him that her father (played by Milo Ventimiglia) has seen every Rocky (1976) movie. This is ironic because Ventimiglia actually played Rocky Balboa's son.

When they were filming the Super Bowl episode in which Jack Pearson dies when Mandy Moore walked into the hospital room she didn't know that her co-star who played Jack Pearson would be lying in the hospital bed

There are a few hints in the pilot that Kevin and Kate are twins and that Randall is their brother. For example, in the scene where Randall gets an email saying that they found his biological father, an email entitled "It's Our Birthday Bro" can be seen in his inbox from Kevin.

In the show, Mandy Moore plays Chrissy Metz's mother. In reality, Chrissy is four years older than Mandy.

Kevin's ex-girlfriend, Sloane, is played by Milana Vayntrub, who also plays the saleswoman from the AT&T Wireless commercials.

The fitness class with green drumsticks (ripstix) Kate takes part in is a real fitness class called Pound-rockout, developed by Kirsten Potenza in Los Angeles. There are classes all over the globe.