The series is National Geographic's first scripted drama series.
Johnny Flynn, who plays the younger Albert Einstein, shares a birthday with the real Einstein. (March 14, 1983).
Both Antonio Banderas and Pablo Picasso were born in Málaga, Spain.
In April 2018, National Geographic renewed the series for a third season set to follow the life of English novelist Mary Shelley, however, in February 2019, it was announced that the subject of the third season would instead be American singer Aretha Franklin, known as "The Queen of Soul".