The Punisher's ally Micro (Ebon Moss-Bachrach) was once mentioned in Agents of S.H.I.E.L.D. (2013) by Skye as a hacker in the Rising Tide group, and later in Daredevil (2015) as a disc with his name on it.

The Punisher made his first appearance in the pages of The Amazing Spider-Man # 129 in February 1974. He was originally going to be a minor second string character due to his penchant for killing, but due to his popularity, he became a more prominent figure in the larger Marvel Universe.

Stan Lee has a cameo in a poster like the other Marvel-Netflix series, but it's brief and very easy to miss.

A special shotgun was made for Amber Rose Revah to use, designed for her height and stature.

In episode 3, Ben Barnes's character is on his cot reading "Picture of Dorian Gray." Ben Barnes played the title character Dorian Gray in 2009.

Marvel and Netflix had to pull the series from the 2017 New York Comic Con panel due to the Las Vegas shooting.

In all shots of the New York skyline the Stark building is missing as it should be near the Empire State Building as it was featured in both Avengers movies and Spider-Man: Homecoming. This is due to the fact that they are considered to be in different "universes".

When Billy Russo is calling for Frank on the radio, Frank's call sign is Raven. In the comics, Frank is a Vietnam vet who is the best at killing and warfare, much like John Rambo, who, when his former colonel is trying to call him on the radio in the movie First Blood is revealed that his call sign is Raven.

Composer Tyler Bates based the series music on blues guitar tunes.

While waiting for Frank in the woods, David (Micro) Lieberman is seen reading the book Life of Pi by Yann Martel. Earlier, when Frank visits Lieberman's house, Leo (Micro's daughter) discusses the book with Frank while repairing the car. She then gives him her copy to read.

Jon Bernthal is the fourth to portray Frank Castle/ The Punisher (in a live-action role). He was played by Dolph Lundgren in 1989, Thomas Jane in 2004, and Ray Stevenson in 2008.

At the end of the first episode Micro says "Welcome back, Frank", a nod to the Garth Ennis/Steve Dillon comic book story which brought the Punisher back to popularity.

Shohreh Aghdashloo and Amber Rose Revah who played mother and daughter on the series also played mother and daughter on the miniseries House of Saddam (2008) which Steve Lightfoot worked as a producer.

Frank Castle is a fan of Earth, Wind and Fire.

Daniel Webber who plays Lewis Wilson previously played a similarly disturbed young man, Lee Harvey Oswald, in 11.22.63 (2016).

Ripley Sobo portrayed Sage in Batman v Superman: Dawn of Justice (2016). This makes her one of the few actresses to date to have appeared in both the Marvel Cinematic Universe and the DC Extended Universe.

Ben Barnes, who plays Billy Russo, played the on-screen father of Charlie Cox in Stardust (2007). Cox appears along with Jon Bernthal in Daredevil (2015).

The photo on the dresser of Dinah Madani's nightstand is a picture of Shohreh Aghdashloo's book cover of her memoir: The Alley of Love and Yellow Jasmines

Brett Mahoney (Royce Johnson) third appearance in Netflix Marvel. Previously seen in Daredevil and Jessica Jones.

This is Shohreh Aghdashloo's second comic-book feature, after X-Men: The Last Stand (2006).

Jon Bernthal (Frank Castle) and Jaime Ray Newman (Sarah Lieberman) worked in 'Eastwick' together and played estranged spouses

Shohreh Aghdashloo is the seventh actress from Star Trek to appear in the Marvel Cinematic Universe after Chris Hemsworth, Idris Elba, Zoe Saldana, Alfre Woodard, Benedict Cumberbatch and Karl Urban.

The two Marvel Cinematic Universe characters to sustain the most wounds during fights and kills are Punisher and Daredevil. While they both lack super powers, their combat skills make them the fiercest. Frank was trained in the Marines while Matt Murdock received his training from his fellow blind mentor, Stick.

Mary Elizabeth Mastrantonio who plays Marion in the show also played another Marian in Robin Hood: Prince of Thieves (1991) opposite Kevin Costner (Robin Hood).

Tim Guinee, who plays Lewis' father Clay Wilson in this, also played another character in the MCU, Major Allen, in Iron Man (2008) and Iron Man 2 (2010).

Both Tony Plana and Shohreh Aghdashloo appeared on 24 (2001)

The second season features Alexa Davalos, who has also starred in The Man in the High Castle, which coincidently similar to the real name of The Punisher, Frank Castle.

This is the first time that Jigsaw/Billy Russo does not appear as he is depicted in the comics: a gangster and mobster. However, he appears as the founding CEO of ANVIL, a private military company. In addition, he appears as Frank's best friend whilst in the comics and in Punisher: War Zone (2008), he is Castle's arch nemesis.

Frank Castle and Billy Russo are shown reading "Moby Dick" and "The Picture of Dorian Gray", respectively. These choices hint at their personalities: much like Captain Ahab, Frank is driven by an obsessive quest for revenge, while Billy puts too much value in his good looks (foreshadowing his final confrontation with Castle, which leaves him permanently disfigured). Ben Barnes, who plays Billy Russo, played Dorian Gray in the 2009 movie, Dorian Gray.

The only Marvel/Netflix series not to feature Rosario Dawson's Claire Temple character so far. Rosario Dawson said on an interview that the producers tried to arrange a cameo but it wasn't possible due to schedule problems.

On episode four, after Castle kills everyone in the warehouse to get the red mustang, you can see a man lying dead on a pinball machine. Diamond Select Toys sells a figurine of the Punisher with a man laying on a Spider-Man pinball machine, which they state they modeled off of art work from Tim Bradstreet.

During the scene where Billy Russo first delivers the rent money to Curtis, Curtis refers to Billy as "a man of wealth and taste." This is the second line from "Sympathy for the Devil" by the Rolling Stones. In the song, this is said by the devil, foreshadowing that Billy will be the antagonist.

Claire Temple (Rosario Dawson) has appeared in five of the six Netflix Marvel shows. She didn't make an appearance in The Punisher while Turk Barrett (Rob Morgan) has appeared in all six. He makes an appearance in Iron Fist season 2.