The pilot episode of The Marvelous Mrs. Maisel was one of Amazon Video's most successful ever, achieving an average viewer rating of 4.9 stars.

On April 10, 2017 Amazon ordered 2 seasons of The Marvelous Mrs. Maisel series. Amy Sherman-Palladino will be in charge again.

Many of the doorposts throughout the series have a small box attached to them. This is a mezuzah, a case containing passages from the Torah (Deuteronomy 6:4-9 and 11:13-21), which Jews traditionally affix to the door frames of their houses as a constant reminder of God's presence. A mezuzah also functions as a sign that a Jewish person occupies the house or works in the building onto which it is affixed, so in this series, the frequent sight of mezuzahs on doorframes is one of many indications that most of the characters are Jewish.

The fortune teller offers a charm filled with "tannis root" which is a fictional herb used by the occult in the film Rosemary's Baby (1968).

The exterior and stairwell of the Gaslight were filmed at Under St. Marks Theatre on St. Marks just off 1st Ave, which is the site of a real open mic that happens every Tuesday from 9pm to 2am.

The show takes place in 1958 from the first episode according to a diary entry.

Rachel Brosnahan's close friend, writer-comedienne Jasmine Pierce, whom she watched make the journey from 'open mic' clubs to writing for The Tonight Show Starring Jimmy Fallon (2014), provided Rachel with ample inspiration and advice for her role in this series.

Amazon's official promotional copy for this series included the fact that Mrs. Maisel has "an elegant Upper West Side apartment perfect for hosting Yom Kippur dinner." For anyone who is Jewish or even remotely knowledgeable about Judaism, this is an odd assertion, since Yom Kippur is the best-known of several fasting observances in the Jewish calendar, and therefore no dinner would be served on the holiday. After Yom Kippur is over, Jewish families do traditionally gather for a meal to break the fast, but this meal is called a "Break-the-Fast," not "Yom Kippur dinner." The meal is referred to correctly in dialogue during the actual pilot episode.

Amy Sherman-Palladino was also the creator of the popular TV series Gilmore Girls (2000). Fans will see some recurring actors and themes in The Marvelous Mrs. Maisel.

Gilmore Girls (2000) fans will remember Alex Borstein, who was originally cast as Sookie, but played Drella, the harp player from the Independence Inn, appearing here as an East Village bar veteran, Susie, who takes Midge under her wing.

Kevin Pollak and Caroline Aaron previously appeared in House Arrest (1996) together.

The typeface used for the title is the same as the one used for the TV show The Osbournes. It called Sparkly and was designed by Stuart Sandler of Font Diner.