Four tubs of fake blood and body parts were used for the scene in which Joel (Timothy Olyphant) and Sheila (Drew Barrymore) dispose of Gary's body. Airbags were inserted into the body parts to keep it light, because the tub actually filled with liquid would be too heavy for the actors to lift.
The scene in the comic book store was filmed at Brave New World Comics in Santa Clarita.
Joel introduces himself as Joel Wichita, a nod to the movie Zombieland (2009) (starring Emma Stone as Wichita) which was also directed by Ruben Fleischer.