Bokeem Woodbine co-starred alongside Tupac in the music video for Tupac's 1996 single "I Ain't Mad At Cha".
Donald Faison plays Haitian Jack in the series and also had a small part in the early Tupac film Juice.
The series also marks the third time Sean Puffy Combs has been played on screen. The first was Derek Luke in Notorious and the second was Shaun Clay in the TLC movie.
This is the second time Luke James has played a real life person. The first time was in the New Edition Story.
The series marks the second time Luke James has portrayed a real life person. The first was Johnny Gill in the New Edition Story.