There is a podcast episode of the Joe Rogan Experience that breaks down supposed inaccuracies in this documentary. In December 2019 James Wilks went on Joe Rogan's show and responded to the criticism and debated Chris Kresser for 4 hours. Joe Rogan was so impressed he said he's considering taking the original show with Kresser offline.

Swami Sri Yukteswar's book, "The Holy Science," which was published back in 1894, devotes Sutras 9-11 in explaining scientifically why vegetarian diet is far more efficient than a meat-based one. He provides comparisons between the digestive systems of herbivores and carnivores, explaining and proving how the human system is like those of herbivores and not carnivores. The information from this documentary film reiterates scientific principles that were presented 125 years ago.