The frame of the screenplay for City of Salt originated from an iambic pentameter poem that Alicia Farmer wrote in 2010 for her English degree called Thisbe's Lover, which was modeled after medieval tragedies and Greek morality plays.

Alicia Farmer wrote City of Salt in 5 days.

Rocky Anderson (presidential candidate, prior mayor of Salt Lake City) plays a Republican senator in City of Salt.

Jim Dabakis, an openly LGBTQ politician and senator, plays a Republican campaign manager in City of Salt.