Based on India's first test tube doctor Starring Pankaj Kapoor, Shabana Azmi and a young Irfan Khan, this movie is loosely based on Dr. Subhash Mukhopadhyay who created the world's second and India's first child using in-vitro fertilisation.
Dr. Mukhopadhyay was harassed by the state government, and not allowed to share his achievements with the international scientific community. Dejected, he committed suicide on 19 June 1981. (From wikipedia)
It was a terrible case of "wrong place, wrong time" for Dr. Mukhopadhyay. The country wanted a solution for population control, and here he was with a solution for fertility. The movie, however, ends on a slightly optimistic note. Wish they had not sugar coated it.