Jennifer Aniston will executive produce and star in Cake, a Black List script about a woman who becomes fascinated with the suicide of a woman in her chronic pain support group. According to a release from the newly forged Cinelou Films Dhj, Aniston’s character, “the acerbic, hilarious Claire Simmons” “uncovers the details of Nina’s suicide and develops a poignant relationship with Nina’s husband.”

“Of the zillions of Jennifer Aniston fans, I might be the biggest one of all,” director Daniel Barnz (Beastly) said, in a statement. “I’ve especially loved her more dramatic performances, and I can...