Production has begun in Boston on the action comedy Central Intelligence, for New Line Cinema and Universal Pictures. The film, starring Dwayne Johnson and Kevin Hart, will be directed by Rawson Marshall Thurber, director of the hit comedies “We’re the Millers” and “Dodgeball.”

The story follows a one-time bullied geek who grew up to be a lethal CIA agent (Johnson), coming home for his high school reunion. Claiming to be on a top-secret case, he enlists the help of the former “big man on campus” (Hart), now an accountant who misses his glory days. But before the staid numbers-cruncher realizes what he’s getting into it’s too late to get out, as his increasingly unpredictable new friend drags him through a world of shoot-outs, double-crosses and espionage that could get them both killed in more ways than he can count.

Central Intelligence will also star Oscar nominee Amy Ryan...