Netflix and Mediaset on Tuesday in Rome announced details of an alliance in Italy under which they will jointly produce seven Italian-language feature films, a move that marks the U.S. streaming giant’s biggest Italian content deal to date.

Five of the films that Netflix will produce in tandem with Italy’s top private generalist broadcaster were announced. They are being made by prominent Italian indie producers such as Indigo Film (“The Great Beauty”) and Lucky Red, with which Netflix teamed up on last year’s Venice title “On My Skin.” All films are to be helmed by young up-and-coming directors.

The films comprise two men’s soccer-related titles, one of which about Roberto Baggio, one of the greatest Italian players of all time, to be directed by female helmer Letizia Lamartire. Lamartire’s comedy, “We’ll Be Young and Beautiful,” about a mother-and-son pop band, was in the...