George Clooney movies have been some of the most prestigious in theaters over the last two decades. Clooney is also one of the most outspoken personalities in the entertainment world, and one of the highest-profile stars as well. His activism, on and off the screen, earns him widespread attention, and his marriage to human rights attorney Amal Alamuddin is often the subject of gossip in Hollywood trade publications and inner circles.

As an actor, Clooney is arguably the best example of one who rose to motion picture stardom after first earning fame on a television series, having portrayed maverick pediatrician Dr. Doug Ross in the first five seasons of ER. Between seasons, Clooney made a name for himself starring in several hit films before switching to big screen roles full-time with 2000's The Perfect Storm. Since then, Clooney has won two Oscars and four Golden Globes over his career, as...