Greys Anatomy has gained a reputation for killing some of its most beloved characters off with some incredibly emotional deaths, and even main characters aren't safe. Greys Anatomy follows the basic premise of medical dramas, focusing on the lives of surgical interns, residents, and attendings as they balance their professional and personal lives, which more often than not overlap and create a lot of drama inside and outside Seattle Grace Hospital (now Grey Sloan Memorial Hospital).

The show is led by Meredith Grey (Ellen Pompeo) alongside other main characters who became audience favorites, many lasting for several years through Grey's Anatomy's 20-season-plus run. Greys Anatomy has become infamous for killing characters when their time on the show is over, and only some lucky few have been given satisfying endings where they got to keep on living. Unfortunately, many of the main Grey's Anatomy characters who were killed off were...