Grey's Anatomy season 17 focused heavily on the Covid-19 pandemic, which divided viewers. The season had memorable moments but was mostly dull. Season 18 marked an improvement with more character development and refreshing crossovers with Station 19. Meredith's journey was particularly strong. Season 19 took risks and introduced new characters, but struggled to find its footing. The season ended with fun and shocking twists, marking the end of an era.

With nearly two decades' worth of Grey's Anatomy seasons in the books, the show has seen its ups and downs in terms of overall quality, with some seasons soaring while others fell. Grey's Anatomy is the mothership of Shondaland Productions, and though other Shondaland shows have indeed been successful, such as How To Get Away With Murder, Scandal, and Private Practice, none lasted as long as Grey's Anatomy. The series helped to reinvent and revitalize the medical drama genre and still has a massive following all these years later.