The Punisher manages to beat Wolverine's healing factor by stabbing him in the neck and electrocuting him, preventing his cells from regenerating. Deadpool kills Wolverine by using a sword made from carbonadium that slows down his healing factor, stabbing him and nullifying his regeneration. X-23 temporarily defeats Wolverine's healing factor by hacking and slashing at him and adding dirt to his wounds, preventing his skin from repairing itself.

Wolverine’s healing factor is perhaps his most useful and most iconic power. Practically any injury he suffers, from gunshot wounds and stabbings to devastating explosions and immense torture, Wolverine can recover from. However, that isn’t to say he’s invincible by any means, as there are a few times in Marvel canon that Wolverine’s healing factor hasn’t been able to save him.

While most enemies don’t have the strength, skills, or intelligence to do so, there...