Galactus detests Deadpool more than prominent heroes, like Reed Richards, after Wade becomes his herald. Deadpool's non-stop chattering as a Herald of Galactus pushes Galactus to his limits, causing him to fire Wade immediately. Galactus' patience snaps due to Deadpool's talking like they're best friends and making pop culture references, turning Deadpool into the rare hero who Galactus simply cannot tolerate.

Marvels Devourer of Worlds, Galactus, is a nigh-omnipotent being who relishes annihilating planets for his own self-benefit, with his hand-picked heralds ensuring that each new world is ready for their inevitable demise when their boss comes knocking. Not particularly fond of many people outside said employees, Galactus is shown to hate one of his temporary heralds even more than the cursed Reed Richards the Merc with a Mouth himself, Deadpool.

Recruiting Silver Surfer into his employ along with many others, like Terrax the Tamer, Morg the Executioner, and even...