Christopher Ciccone, an artist, interior designer and Madonna’s younger brother, died Friday, The Hollywood Reporter has learned. He was 63.

Ciccone had been battling cancer and died peacefully, surrounded by his husband, Ray Thacker, and other loved ones, according to a statement from Ciccone’s rep.

Ciccone, who got his start as a dancer and choreographer, used his talents to support Madonna’s emerging career, becoming dresser and creative consultant to his superstar sister. He also directed music videos and tours, including Madonna’s The Girlie Show world tour in 1993. And he was the art director for her 1990 Blond Ambition World Tour.

He went on to work as an interior, footwear and furniture designer and artist and wrote the 2008 best-selling book Life With My Sister Madonna, which led to reports that the siblings had had a falling-out.

Ciccone claimed Madonna outed him in a 1991 interview with The Advocate, where she identified him as “gay,...