The Pradeeps of Pittsburgh follows an Indian family who packs up their lives and moves to Pittsburgh, Pennsylvania. Loosely inspired by the real-life experiences of show creator Vijal Patel, The Pradeeps of Pittsburgh adds a unique serialized mystery twist. The show is told mainly in flashbacks, with the Pradeep family and their neighbors being interviewed by federal agents investigating a community-shaking arson crime.

The patriarch of the Pradeep clan, Mahesh, is played by Naveen Andrews, best known for his roles in The English Patient and the hit ABC drama Lost. Meanwhile, the neighbor family is led by Jimbo, played by My Name Is Earl and Mallrats veteran Ethan Suplee. While ostensibly the heads of their households, they serve at the convenience of their more powerful and headstrong wives, played by Sindhu Vee and Megan Hilty, respectively.

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